ACCURETIC is a prescription medication developed by Pfizer, primarily used for the management of hypertension (high blood pressure) and heart failure. Combining two active ingredients, this drug offers a dual approach to controlling blood pressure, making it a valuable option for patients struggling with these conditions. Here we explore the formulation, uses, advantages, side effects, dosage, precautionary measures, and relevant pricing of ACCURETIC in the UK and US.
Formulation of ACCURETIC
ACCURETIC is a combination medication that contains two main components:
- Hydrochlorothiazide– a thiazide diuretic that helps reduce fluid retention and lowers blood pressure.
- Quinapril– an angiotensin-converting enzyme (ACE) inhibitor that relaxes blood vessels, improving blood flow and further aiding in blood pressure reduction.
The formulation is available in tablet form, typically in strengths of 10 mg/12.5 mg and 20 mg/12.5 mg of quinapril/hydrochlorothiazide.
Uses of ACCURETIC
ACCURETIC is primarily prescribed for:
- Hypertension: To help lower blood pressure and reduce the risk of cardiovascular complications.
- Heart Failure: To improve symptoms associated with heart failure and enhance the quality of life.
The combination of an ACE inhibitor and a diuretic is particularly effective for patients with resistant hypertension or those who require multiple medications to achieve optimal blood pressure control.
Advantages of ACCURETIC
- Dual Action: The combination of hydrochlorothiazide and quinapril provides enhanced efficacy compared to single-agent therapies.
- Convenience: Taking one pill instead of multiple medications can improve patient adherence.
- Cardiovascular Benefits: Helps reduce the risk of strokes, heart attacks, and kidney issues associated with high blood pressure.
Side Effects of ACCURETIC
While ACCURETIC is effective, it can also lead to some side effects, which may include:
- Dizziness or lightheadedness
- Fatigue
- Cough (common with ACE inhibitors)
- Low potassium levels (hypokalemia)
- Allergic reactions, including rash or swelling
Patients should consult their healthcare provider if they experience severe side effects or any unusual symptoms.
Dosage of ACCURETIC
The typical starting dose of ACCURETIC is determined by the physician based on the patient’s condition and response to treatment. Dosage may be adjusted as needed, but it generally ranges from:
- 10 mg/12.5 mg to 40 mg/25 mg daily, taken once or twice, with or without food.
It’s essential for patients to follow their healthcare provider’s instructions regarding dosage to ensure safe and effective treatment.
Precautionary Measures of ACCURETIC
Patients should consider the following precautions:
- Allergic Reactions: Inform your doctor about any previous allergic reactions to ACE inhibitors or sulfonamide-derived medications.
- Kidney Function: Regular monitoring of kidney function is recommended, especially in patients with pre-existing renal issues.
- Pregnancy and Breastfeeding: ACCURETIC is not recommended during pregnancy due to potential harm to the fetus. Breastfeeding mothers should also discuss alternatives with their healthcare provider.
- Electrolyte Levels: Periodic blood tests may be necessary to monitor electrolyte levels, particularly potassium.
Year of Invention & Company Information
ACCURETIC was developed by Pfizer, a global leader in the pharmaceutical industry known for its commitment to research and innovation. Pfizer was founded in 1849 and has since become a major player in the development of a wide range of medications, including vaccines and treatments for chronic diseases.
Price of ACCURETIC in UK & US
The price of ACCURETIC can vary significantly based on the pharmacy, location, and insurance coverage. As of the latest information:
- In the United States: The average retail price for a 30-day supply of ACCURETIC ranges from $150 to $200, though it may be lower with insurance.
- In the United Kingdom: The cost is generally lower, with a 28-day supply priced around £40 to £60, depending on the pharmacy.
Conclusion
ACCURETIC represents a significant advancement in the treatment of hypertension and heart failure, providing a comprehensive solution through its dual-action formulation. While it offers numerous benefits, patients should remain aware of potential side effects and adhere to precautionary measures. As with any medication, consulting with a healthcare provider is crucial for safe and effective treatment. Pfizer’s ongoing commitment to innovation ensures that ACCURETIC will continue to be a valuable tool in managing cardiovascular health for years to come.
