ARTHROTEC is a pharmaceutical product developed by Pfizer, primarily used for the management of pain associated with arthritis and other inflammatory conditions. It combines two active ingredients: diclofenac, a non-steroidal anti-inflammatory drug (NSAID), and misoprostol, a synthetic prostaglandin. This combination not only alleviates pain and inflammation but also protects the gastrointestinal lining, reducing the risk of ulcers associated with NSAID use. Here we explore the formulation, uses, advantages, side effects, dosage, precautionary measures, and relevant pricing of ARTHROTEC in the UK and US.
Formulation of ARTHROTEC
ARTHROTEC is formulated as a tablet that contains 50 mg of diclofenac sodium and 200 mcg of misoprostol. The combination allows for effective pain relief while minimizing gastrointestinal side effects, a common concern with NSAID treatments.
Uses of ARTHROTEC
ARTHROTEC is primarily indicated for:
- Management of osteoarthritis
- Rheumatoid arthritis
- Pain associated with other inflammatory conditions
It is particularly beneficial for patients who have a history of NSAID-induced gastric ulcers or those who are at a high risk of developing them.
Advantages of ARTHROTEC
- Dual Action: Provides anti-inflammatory effects while protecting the stomach lining.
- Reduced Gastrointestinal Risks: The inclusion of misoprostol helps mitigate common side effects of NSAIDs, such as gastrointestinal bleeding and ulcers.
- Effective Pain Relief: Offers significant relief for arthritis-related pain, improving quality of life.
Side Effects of ARTHROTEC
Like any medication, ARTHROTEC may cause side effects, including:
- Diarrhea
- Abdominal pain
- Nausea
- Headache
- Dizziness
- Elevated liver enzymes
Patients are advised to report any severe or persistent side effects to their healthcare provider.
Dosage of ARTHROTEC
The typical dosage for ARTHROTEC is one tablet taken two to three times a day, as directed by a healthcare professional. It is important to follow the prescribed dosage to minimize the risk of side effects and ensure effective treatment.
Precautionary Measures of ARTHROTEC
- Contraindications: ARTHROTEC should not be used in patients with known hypersensitivity to diclofenac, misoprostol, or any component of the formulation.
- Pregnancy: Misoprostol can cause uterine contractions; hence, ARTHROTEC is contraindicated in pregnancy.
- Gastrointestinal History: Patients with a history of gastrointestinal disorders should consult their doctor before use.
- Kidney and Liver Function: Regular monitoring is essential for patients with impaired renal or hepatic function.
Year of Invention & Company Information
ARTHROTEC was developed in the 1990s and has since become a key product in Pfizer’s portfolio. Pfizer, a leading global pharmaceutical company, is dedicated to the research and development of innovative medicines and vaccines, aiming to improve health outcomes worldwide.
Price of ARTHROTEC in UK & US
In the United States, the price of ARTHROTEC typically ranges from $200 to $300 for a 30-day supply, depending on the pharmacy and insurance coverage. In the United Kingdom, it is available for approximately £60 to £90 for a similar supply, though prices may vary based on the pharmacy and region.
Conclusion
ARTHROTEC represents a significant advancement in the management of arthritis pain, particularly for patients at risk of NSAID-induced gastrointestinal complications. With its unique formulation and dual-action mechanism, it provides effective relief while promoting gastrointestinal safety. However, it is essential for patients to be aware of potential side effects and contraindications. As with any medication, consultation with a healthcare provider is crucial for safe and effective use.
