STROMECTOL® is a prescription medication developed by Merck & Co., Inc., containing the active ingredient Ivermectin. Ivermectin is a broad-spectrum antiparasitic agent used to treat various parasitic infections. Initially developed for veterinary use, it has become an important treatment for several human parasitic diseases due to its effectiveness and safety profile. Here we will cover its formulation, uses, advantages, side effects, dosage, precautionary measures, year of invention, company information, and pricing in the UK and USA.
Formulation of STROMECTOL®(Ivermectin)
STROMECTOL® tablets are available in a single strength:
- Ivermectin 3 mg
The tablets are typically supplied in a blister pack and should be taken orally with water. The formulation ensures that the medication is absorbed efficiently to exert its therapeutic effects.
Uses of STROMECTOL®(Ivermectin)
STROMECTOL® is used to treat a range of parasitic infections. Its primary indications include:
- Onchocerciasis (River Blindness): A parasitic disease caused by the worm Onchocerca volvulus. It can lead to severe itching, skin conditions, and in some cases, blindness.
- Lymphatic Filariasis: Caused by parasitic worms, this disease can lead to severe swelling and disability in the limbs and genital region.
- Strongyloides Stercoralis Infection: An infection caused by the parasitic worm Strongyloides stercoralis, which can lead to gastrointestinal symptoms and other complications.
- Scabies: A skin infestation caused by the mite Sarcoptes scabiei, leading to intense itching and rash.
- Pediculosis: Head lice infestations that cause itching and discomfort.
Advantages of STROMECTOL®(Ivermectin)
- Broad Spectrum: Ivermectin is effective against a variety of parasitic infections, making it a versatile treatment option.
- Single-Dose Regimen: For many conditions, a single dose of STROMECTOL® is sufficient to clear the infection, simplifying the treatment process for patients.
- Well-Tolerated: STROMECTOL® has a generally favorable safety profile, and side effects are typically mild and transient.
- Safe for Use in Humans: Although originally developed for veterinary use, STROMECTOL® has been extensively studied and proven safe and effective for treating human parasitic infections.
Side Effects of STROMECTOL®(Ivermectin)
STROMECTOL® is generally well-tolerated, but like all medications, it can cause side effects. Common side effects include:
- Dizziness
- Nausea
- Diarrhea
- Abdominal pain
- Fatigue
- Rash
Serious Side Effects (Less Common):
- Severe Allergic Reactions: Symptoms like difficulty breathing, swelling of the face or throat, and severe rash may occur.
- Neurological Effects: Rarely, some patients may experience dizziness, confusion, or tremors.
Dosage of STROMECTOL®(Ivermectin)
- Onchocerciasis: A single dose of 150-200 mcg/kg of body weight.
- Lymphatic Filariasis: A single dose of 200 mcg/kg.
- Strongyloides Stercoralis: Typically requires a single dose, with repeat dosing possible based on clinical response.
- Scabies and Pediculosis: A single dose may be sufficient, with a second dose given after a week if needed.
Precautionary Measures of STROMECTOL®(Ivermectin)
- Pregnancy: The safety of Ivermectin during pregnancy is not well-established. It should be used only if clearly needed and prescribed by a healthcare provider.
- Breastfeeding: The excretion of Ivermectin in breast milk is unknown, so caution is advised when using STROMECTOL® while breastfeeding.
- Liver Disease: Patients with severe liver disease should use Ivermectin cautiously, as it may affect drug metabolism.
- Drug Interactions: Ivermectin may interact with certain medications, so it’s important to inform your healthcare provider of all medications and supplements you are taking.
- Renal Impairment: Caution is advised in patients with severe renal impairment.
Year of Information of STROMECTOL®(Ivermectin)
STROMECTOL® (ivermectin) was approved by the FDA in 1996. However, ivermectin itself was discovered in the late 1970s and was developed from a compound isolated from a soil bacterium. The drug has since been widely used for various parasitic infections.
Company Information of STROMECTOL®(Ivermectin)
Merck & Co., Inc. is a global healthcare company known for its commitment to developing innovative therapies across various therapeutic areas. Merck has a long history of excellence in pharmaceuticals and vaccines. STROMECTOL® was first approved for human use in the late 1980s.
- Headquarters: Rahway, New Jersey, USA
- Year of Invention: STROMECTOL® was first approved by the FDA in 1996.
Price in USA and UK of STROMECTOL®(Ivermectin)
The cost of STROMECTOL® can vary significantly based on location, pharmacy, and insurance coverage:
- In the USA: The price for a 3 mg tablet of STROMECTOL® is generally around $50 to $100, depending on the pharmacy and insurance coverage.
- In the UK: The cost is generally lower due to the National Health Service (NHS) subsidies. On average, a month’s supply may cost approximately £30 to £40, though NHS patients may receive it at a subsidized rate or free.
Conclusion
STROMECTOL® (Ivermectin) tablets by Merck are a powerful tool in the fight against various parasitic infections. With its broad-spectrum activity and generally favorable safety profile, it has become a standard treatment for conditions like onchocerciasis, lymphatic filariasis, and scabies. While it offers many advantages, including effective single-dose treatment, patients should be aware of potential side effects and precautions. Always consult with a healthcare provider for proper diagnosis and treatment tailored to individual needs.